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Article

Gene Expression and Alternative Splicing Analysis in a Large-Scale Multiple Sclerosis Study.

International journal of molecular sciences - 7 Nov 2024

Sak Müge, Chariker Julia H, Park Juw Won, Rouchka Eric Christian

Abstract excerpt

Multiple Sclerosis (MS) is an autoimmune neurodegenerative disease affecting approximately 3 million people globally. Despite rigorous research on MS, aspects of its development and progression remain unclear. We utilized a publicly available RNA-seq dataset (GSE138614) consisting of the post-mortem white matter tissues of five donors without any neurological disorders and ten MS patient donors. We investigated...

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Identifiers

PMID: 39596026
DOI: 10.3390/ijms252211957
PMCID: PMC11593658

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