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Article

The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis.

Journal of autoimmunity - 1 Mar 2017

Fewings N L, Gatt P N, McKay F C, Parnell G P, Schibeci S D, Edwards J, Basuki M A, Goldinger A, Fabis-Pedrini M J, Kermode A G, Manrique C P, McCauley J L, Nickles D, Baranzini S E, Burke T, Vucic S, Stewart G J, Booth D R

Abstract excerpt

Multiple Sclerosis (MS) is a neurological condition driven in part by immune cells from the peripheral circulation, the targets for current successful therapies. The autoimmune and MS risk gene ZMIZ1 is underexpressed in blood in people with MS. We show that, from three independent sets of transcriptomic data, expression of ZMIZ1 is tightly correlated with that of hundreds of other genes. Further we show...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28063629
DOI: 10.1016/j.jaut.2016.12.006

Genes

ZMIZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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