Article
K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines.
The American journal of pathology - 1 Oct 1996
Erill N, Cuatrecasas M, Sancho F J, Farré A, Pour P M, Lluís F, Capellá G
Abstract excerpt
K-ras and p53 gene alterations are frequently found in human pancreatic carcinomas and cell lines. The aim of this study was to analyze for the presence of K-ras and p53 gene mutations in hamster pancreatic tumors and cell lines. Mutations at the first coding exon of the K-ras gene and in exons V...
Topics
- Animals
- Carcinogens
- Carcinoma, Ductal, Breast
- Cricetinae
- Genes, p53
- Genes, ras
- Mutation
- Nitrosamines
- Pancreatic Neoplasms
- Polymorphism, Single-Stranded Conformational
- Tumor Cells, Cultured