Article
K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines.
The American journal of pathology - 1 Oct 1996
Erill N, Cuatrecasas M, Sancho F J, Farré A, Pour P M, Lluís F, Capellá G
Abstract excerpt
K-ras and p53 gene alterations are frequently found in human pancreatic carcinomas and cell lines. The aim of this study was to analyze for the presence of K-ras and p53 gene mutations in hamster pancreatic tumors and cell lines. Mutations at the first coding exon of the K-ras gene and in exons V to VIII of the hamster p53 gene were analyzed in six cell lines (H2T, PC1, PC1.2, PC1.0, WD, and PD) and in...
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