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Twenty-one proteins up-regulated in human H-ras oncogene transgenic rat pancreas cancers are up-regulated in human pancreas cancer.

Pancreas - 1 Aug 2013

Yabushita Setsuko, Fukamachi Katsumi, Kikuchi Fumitake, Ozaki Masakazu, Miyata Kaori, Sukata Tokuo, Deguchi Yoshihito, Tanaka Hajime, Kakehashi Anna, Kawamura Satoshi, Uwagawa Satoshi, Wanibuchi Hideki, Suzui Masumi, Alexander David B, Tsuda Hiroyuki

Abstract excerpt

OBJECTIVES: We have established rat models of pancreatic ductal adenocarcinoma (PDAC) in which expression of a human H-ras(G12V) or K-ras(G12V) oncogene regulated by the Cre/lox system drives pancreatic carcinogenesis. Pancreatic ductal adenocarcinoma which develops in H-ras(G12V) and K-ras(G12V) transgenic rats is cytogenetically and histopathologically similar to human PDAC. The present study was designed to...

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Identifiers

PMID: 23648844
DOI: 10.1097/MPA.0b013e3182883624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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