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African Mitochondrial DNA Subhaplogroups and Peripheral Neuropathy during Antiretroviral Therapy

19 Apr 2010

Abstract excerpt

Susceptibility to peripheral neuropathy during antiretroviral therapy with nucleoside reverse-transcriptase inhibitors was previously associated with a European mitochondrial DNA (mtDNA) haplogroup among non-Hispanic white persons. To determine whether nucleoside reverse-transcriptase inhibitor-associated peripheral neuropathy was related to mtDNA variation in non-Hispanic black persons, we sequenced mtDNA of...

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PMID: 20402593
DOI: 10.1086/652419

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