Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial genomics and antiretroviral therapy-associated metabolic complications in HIV-infected Black South Africans: a pilot study.

AIDS research and human retroviruses - 1 Jul 2013

Sinxadi Phumla Z, Dave Joel A, Samuels David C, Heckmann Jeannine M, Maartens Gary, Levitt Naomi S, Wester C William, Haas David W, Hulgan Todd

Abstract excerpt

Studies suggest that mitochondrial DNA (mtDNA) haplogroups are associated with antiretroviral therapy (ART)-related metabolic complications and distal sensory polyneuropathy (DSP), but there have been few studies in persons of African descent. We explored such associations in South African adults. Clinical and laboratory data and DNA specimens from a cross-sectional study were used. Sequencing and Phylotree...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Mitochondrial

Share to Hypertriglyceridemia

Share to Metabolic Diseases

Share to Pilot Projects

Share to Polyneuropathies

Share to South Africa

Source

Open in PubMed Open full text

Identifiers

PMID: 23428049
DOI: 10.1089/aid.2012.0373
PMCID: PMC3685683

Genes

DSP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial genomics and antiretroviral therapy-associated metabolic complications in HIV-infected Black South Africans: a pilot study.PMID 23428049Read ↗

European mitochondrial DNA haplogroups and metabolic changes during antiretroviral therapy in AIDS Clinical Trials Group Study A5142*Semantic proximity Read ↗

African Mitochondrial DNA Subhaplogroups and Peripheral Neuropathy during Antiretroviral TherapySemantic proximity Read ↗

Mitochondrial subhaplogroups and differential risk of stavudine-induced lipodystrophy in Malawian HIV/AIDS patients.Semantic proximity Read ↗

Mitochondrial DNA subhaplogroups L0a2 and L2a modify susceptibility to peripheral neuropathy in malawian adults on stavudine containing highly active antiretroviral therapy.Semantic proximity Read ↗

Mitochondrial DNA variation and changes in adiponectin and endothelial function in HIV-infected adults after antiretroviral therapy initiation.Semantic proximity Read ↗

Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy.Semantic proximity Read ↗

Mitochondrial genomics and CD4 T-cell count recovery after antiretroviral therapy initiation in AIDS clinical trials group study 384.Semantic proximity Read ↗

Non-alcoholic fatty liver disease in people living with HIVSemantic proximity Read ↗

Contribution of APOA5, APOC3, CETP, ABCA1 and SIK3 genetic variants to hypertriglyceridemia development in Mexican HIV-patients receiving antiretroviral therapy.Semantic proximity Read ↗

Risk factors for fatty liver in the Multicenter AIDS Cohort Study.Semantic proximity Read ↗

APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans.Semantic proximity Read ↗

Interaction of Antiretroviral Drugs with the Microbiome & Implications on the development of cardiovascular diseases in HIV+ persons: A Study ProtocolSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.