Article
Pheromone signaling mechanisms in yeast: a prototypical sex machine.
Science (New York, N.Y.) - 26 Nov 2004
Wang Yuqi, Dohlman Henrik G
Abstract excerpt
The actions of many extracellular stimuli are elicited by complexes of cell surface receptors, heterotrimeric guanine nucleotide-binding proteins (G proteins), and mitogen-activated protein (MAP) kinase complexes. Analysis of haploid yeast cells and their response to peptide mating pheromones has produced important advances in our understanding of G protein and MAP kinase signaling mechanisms. Many of the...
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