Article
Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.
Current biology : CB - 21 Mar 2006
Lamson Rachel E, Takahashi Satoe, Winters Matthew J, Pryciak Peter M
Abstract excerpt
Distinct MAP kinase pathways in yeast share several signaling components , including the PAK Ste20 and the MAPKKK Ste11, yet signaling is specific. Mating pheromones trigger an initial step in which Ste20 activates Ste11 , and this requires plasma membrane recruitment of the MAP kinase cascade sc...
Topics
- Adaptor Proteins, Signal Transducing
- Cell Membrane
- Intracellular Membranes
- MAP Kinase Signaling System
- Models, Biological
- Mutation
- Plasmids
- Protein Structure, Tertiary
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins