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Article

MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast.

Nature - 1 Mar 2007

Paliwal Saurabh, Iglesias Pablo A, Campbell Kyle, Hilioti Zoe, Groisman Alex, Levchenko Andre

Abstract excerpt

The mating pathway in Saccharomyces cerevisiae has been the focus of considerable research effort, yet many quantitative aspects of its regulation still remain unknown. Using an integrated approach involving experiments in microfluidic chips and computational modelling, we studied gene expression and phenotypic changes associated with the mating response under well-defined pheromone gradients. Here we report a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17310144
DOI: 10.1038/nature05561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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