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Article

Mitogen-activated protein kinase (MAPK) dynamics determine cell fate in the yeast mating response.

The Journal of biological chemistry - 15 Dec 2017

Li Yang, Roberts Julie, AkhavanAghdam Zohreh, Hao Nan

Abstract excerpt

In the yeast Saccharomyces cerevisiae, the exposure to mating pheromone activates a prototypic mitogen-activated protein kinase (MAPK) cascade and triggers a dose-dependent differentiation response. Whereas a high pheromone dose induces growth arrest and formation of a shmoo-like morphology in yeast cells, lower pheromone doses elicit elongated cell growth. Previous population-level analysis has revealed that the...

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Identifiers

PMID: 29123025
DOI: 10.1074/jbc.AC117.000548
PMCID: PMC5733576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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