Article
Plasma endothelin-1 and single nucleotide polymorphisms of endothelin-1 and endothelin type A receptor genes as risk factors for normal tension glaucoma.
Molecular vision - 1 Jan 2016
Kosior-Jarecka Ewa, Wróbel-Dudzińska Dominika, Łukasik Urszula, Aung Tin, Khor Chiea Chuen, Kocki Janusz, Żarnowski Tomasz
Abstract excerpt
PURPOSE: The purpose of this study was to determine whether four single nucleotide polymorphisms (SNPs) of endothelin and endothelin receptor type A genes can constitute a risk factor for normal tension glaucoma (NTG) and high tension glaucoma (HTG). METHODS: The study included 160 patients with NTG, 124 patients with HTG, and 165 healthy controls. To analyze the frequency of polymorphic variants of the...
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