Article
Investigations on the association between normal tension glaucoma and single nucleotide polymorphisms of the endothelin-1 and endothelin receptor genes.
Molecular vision - 29 Aug 2006
Kim Seok Hwan, Kim Ji Yeon, Kim Dong Myung, Ko Hyun Su, Kim Sung Yeun, Yoo Taiwoo, Hwang Seung Sik, Park Sung Sup
Abstract excerpt
PURPOSE: In normal tension glaucoma (NTG), intraocular pressure is within normal the range; thus, some mechanism other than increased pressure contributes to the optic neuropathy. Endothelin may be an important contributor to the development of the optic neuropathy characteristic of glaucoma. We investigated whether polymorphisms of the endothelin-1, endothelin receptor type A, and endothelin receptor type B...
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