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Article

Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with sex and postmenopausal hormone use.

Investigative ophthalmology & visual science - 1 Feb 2010

Kang Jae Hee, Wiggs Janey L, Rosner Bernard A, Hankinson Susan E, Abdrabou Wael, Fan Bao Jian, Haines Jonathan, Pasquale Louis R

Abstract excerpt

PURPOSE: To evaluate the association between the nitric oxide synthase gene (NOS3) variants and primary open-angle glaucoma (POAG). METHODS: Two functional single-nucleotide polymorphisms (SNPs) (T-786C: rs2070744; Glu298Asp: rs1799983) and three tagging SNPs (rs7830, rs3918188, and rs1800779) were evaluated in a nested case-control study from the Nurses' Health Study (1980-2002) and the Health Professionals'...

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Share to Nitric Oxide Synthase Type III
Share to Polymorphism, Single Nucleotide
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Source

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Identifiers

PMID: 19815736
DOI: 10.1167/iovs.09-4266
PMCID: PMC3094851

Genes

NOS3

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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