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Article

Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit.

European journal of pharmacology - 10 Jul 2010

Choi Sun-Hye, Shin Tae-Joon, Lee Byung-Hwan, Chu Dae-hyun, Choe Han, Pyo Mi-Kyung, Hwang Sung-Hee, Kim Bo-Ra, Lee Sang-Mok, Lee Jun-Ho, Kim Dong-Hyun, Kim Hyoung-Chun, Rhim Hye-whon, Nah Seung-Yeol

Abstract excerpt

The slowly activating delayed rectifier K(+) channels (I(Ks)) are one of the main pharmacological targets for development of drugs against cardiovascular diseases. Cardiac I(Ks) consists of KCNQ1 plus KCNE1 subunits. Ginsenoside, one of the active ingredient of Panax ginseng, enhances cardiac I(Ks) currents. However, little is known about the molecular mechanisms of how ginsenoside interacts with channel proteins...

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Source

Identifiers

PMID: 20399767
DOI: 10.1016/j.ejphar.2010.04.001

Genes

KCNQ1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit.PMID 20399767Read ↗

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