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Article

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel.

The EMBO journal - 1 Dec 2000

Tinel N, Diochot S, Borsotto M, Lazdunski M, Barhanin J

Abstract excerpt

Mutations in HERG and KCNQ1 (or KVLQT1) genes cause the life-threatening Long QT syndrome. These genes encode K(+) channel pore-forming subunits that associate with ancillary subunits from the KCNE family to underlie the two components, I(Kr) and I(Ks), of the human cardiac delayed rectifier current I(K). The KCNE family comprises at least three members. KCNE1 (IsK or MinK) recapitulates I(Ks) when associated...

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Source

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Identifiers

PMID: 11101505
DOI: 10.1093/emboj/19.23.6326
PMCID: PMC305874

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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