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Article

In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart

23 Mar 2005

Abstract excerpt

OBJECTIVE: The voltage-gated K+ channel KCNQ1 associates with the small KCNE1 beta subunit to underlie the IKs repolarizing current in the heart. Based on sequence homology, the KCNE family is recognized to comprise five members. Controversial data have indicated their participation in several K+ channel protein complexes, including KCNQ1. The expression level and the putative functions of the different KCNE...

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Share to Cardiac Arrhythmias and Treatments
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Identifiers

PMID: 16039274
DOI: 10.1016/j.cardiores.2005.02.014

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