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Article

Association Between Period 3 Gene Polymorphisms and Adverse Effects of Antidepressants for Major Depressive Disorder.

Genetic testing and molecular biomarkers - 1 Dec 2019

Xu Yifan, Ma Huiying, Zhao Ting, Wen Dan, Wen Yujiao, Qiao Dan, Liu Zhifen

Abstract excerpt

Aims: Circadian rhythm genes including Period 3 (Per3) are associated with major depressive disorder (MDD) and have an effect on the patient's response to selective serotonin reuptake inhibitor (SSRI) antidepressants. The aim of this study was to identify possible associations between three single nucleotide polymorphisms (SNPs) of Per3 (rs10746473, rs228697, and rs228729), the MDD symptoms, and adverse effects...

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Source

Identifiers

PMID: 31692380
DOI: 10.1089/gtmb.2019.0065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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