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A genome-wide association study identifies candidate genes for sleep disturbances in depressed individuals.

Human genomics - 22 May 2024

Yang Xuena, Cheng Bolun, Cheng Shiqiang, Liu Li, Pan Chuyu, Meng Peilin, Li Chun'e, Chen Yujing, Zhang Jingxi, Zhang Huijie, Zhang Zhen, Wen Yan, Jia Yumeng, Liu Huan, Zhang Feng

Abstract excerpt

OBJECTIVE: This study aimed to identify candidate loci and genes related to sleep disturbances in depressed individuals and clarify the co-occurrence of sleep disturbances and depression from the genetic perspective. METHODS: The study subjects (including 58,256 self-reported depressed individuals and 6,576 participants with PHQ-9 score ≥ 10, respectively) were collected from the UK Biobank, which were determined...

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Identifiers

PMID: 38778419
DOI: 10.1186/s40246-024-00609-5
PMCID: PMC11110369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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