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Article

Association analyses of the autosomal genome and mitochondrial DNA with accelerometry-derived sleep parameters in depressed UK biobank subjects.

Journal of psychiatric research - 1 Jan 2023

Melhuish Beaupre Lindsay M, Wainberg Michael, Zai Clement C, Milic Milos, Felsky Daniel, Brown Gregory, Goldstein Benjamin I, Tripathy Shreejoy J, Kennedy James L, Gonçalves Vanessa F

Abstract excerpt

BACKGROUND: The bidirectional relationship between sleep disturbances and depression is well documented, yet the biology of sleep is not fully understood. Mitochondria have become of interest not only because of the connection between sleep and metabolism but also because of mitochondria's involvement in the production of reactive oxygen species, which are largely scavenged during sleep. METHODS: Genome-wide...

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PMID: 36463630
DOI: 10.1016/j.jpsychires.2022.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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