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Genetics of the type I interferon pathway in systemic lupus erythematosus

15 Nov 2013

Abstract excerpt

Genetic studies of systemic lupus erythematosus (SLE) have been successful, identifying numerous risk factors for human disease. While the list is not yet complete, it is clear that important immune system pathways are represented, one of which being type I interferon (IFN). Circulating type I IFN levels are high in SLE patients and this IFN pathway activation is heritable in families with SLE. We summarize our...

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PMID: 24416080
DOI: 10.2217/ijr.13.58

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