Article
An update on the role of type I interferons in systemic lupus erythematosus and Sjögren's syndrome.
Current opinion in rheumatology - 1 Sept 2018
Thorlacius Gudny Ella, Wahren-Herlenius Marie, Rönnblom Lars
Abstract excerpt
PURPOSE OF REVIEW: Systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS) share several clinical and laboratory features, including an overexpression of type I interferon (IFN) regulated genes. The genetic background to this IFN signature and the role of the type I IFN system in the disease process have been partly clarified. Here, we summarize the latest information concerning the type I IFN...
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