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Article

Heme oxygenase 1 polymorphisms and plasma concentrations in critically ill patients.

Shock (Augusta, Ga.) - 1 Dec 2010

Saukkonen Katri, Lakkisto Päivi, Kaunisto Mari A, Varpula Marjut, Voipio-Pulkki Liisa-Maria, Varpula Tero, Pettilä Ville, Pulkki Kari

Abstract excerpt

Heme oxygenase 1 (HO-1) is a cytoprotective enzyme upregulated by various critical illness-related stress stimuli. We investigated the association of HO-1 gene polymorphisms and plasma concentrations with the outcome of critically ill patients in a prospective cohort study of 231 critically ill patients admitted to tertiary care medical and medical-surgical intensive care units. Blood samples were collected on...

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PMID: 20386498
DOI: 10.1097/SHK.0b013e3181e14de9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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