Article
Erythrocyte SOD1 activity, but not SOD1 polymorphisms, is associated with ICU mortality in patients with septic shock.
Free radical biology & medicine - 20 Aug 2018
Costa Nara Aline, Cunha Natália Baraldi, Gut Ana Lucia, Azevedo Paula Schmidt, Polegato Bertha Furlan, Zornoff Leonardo Antonio Mamede, de Paiva Sergio Alberto Rupp, Reis Bruna Zavarize, Fernandes Ana Angelica Henrique, Rogero Marcelo Macedo, Norde Marina Maintinguer, Minicucci Marcos Ferreira
Abstract excerpt
The objective of our study was to evaluate the influence of the superoxide dismutase 1 (SOD1) polymorphisms on erythrocyte SOD1 activity and the mortality of patients with septic shock. We prospectively evaluated 175 patients aged over 18 years with septic shock upon ICU admission. However, 38 patients were excluded. Thus, 137 patients were enrolled in the study. Blood samples were taken within the first 24 h of...
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