Article
Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism.
Annals of medicine - 1 Apr 2010
Ruchat Stephanie-May, Vohl Marie-Claude, Weisnagel S John, Rankinen Tuomo, Bouchard Claude, Pérusse Louis
Abstract excerpt
BACKGROUND: Although several candidate gene polymorphisms (SNPs) have been associated with increased risk of type 2 diabetes mellitus (T2DM), relatively few studies have assessed the ability of T2DM candidate genes to assess the risk of impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and T2DM beyond the information provided by clinical risk factors. OBJECTIVE: To test whether the inclusion of...
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