Article
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.
Diabetes - 1 Nov 2008
van Hoek Mandy, Dehghan Abbas, Witteman Jacqueline C M, van Duijn Cornelia M, Uitterlinden André G, Oostra Ben A, Hofman Albert, Sijbrands Eric J G, Janssens A Cecile J W
Abstract excerpt
OBJECTIVE: Prediction of type 2 diabetes based on genetic testing might improve identification of high-risk subjects. Genome-wide association (GWA) studies identified multiple new genetic variants that associate with type 2 diabetes. The predictive value of genetic testing for prediction of type 2 diabetes in the general population is unclear. RESEARCH DESIGN AND METHODS: We investigated 18 polymorphisms from...
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