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Article

No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia.

Psychiatry research - 30 May 2010

Zhang Chen, Fang Yiru, Xie Bin, Cheng Wenhong, Du Yasong, Wang Dongxiang, Yu Shunying

Abstract excerpt

Decreased dopaminergic activity in the prefrontal cortex (PFC) has been consistently reported in schizophrenia patients. The dopamine D1 receptor (DRD1) plays an important role in mediating dopaminergic transmission in the PFC. Controversy about this topic still exists despite ample evidence suggesting that the DRD1 gene is associated with performance on neuropsychological tests probing the function of the PFC in...

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Source

Identifiers

PMID: 20382433
DOI: 10.1016/j.psychres.2009.12.011

Genes

DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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