Article
[Association analysis between dopamine D1 receptor gene and symptom quantitative trait of schizophrenia].
Zhonghua yi xue za zhi - 9 Aug 2011
Zhang Chen, Wu Zhi-guo, Shao Yang, Li Ze-zhi, Yu Shun-ying, Fang Yi-ru
Abstract excerpt
OBJECTIVE: To explore the relationship between dopamine D1 receptor gene (DRD1) and symptom quantitative trait of schizophrenia. METHODS: Peripheral blood samples were collected from 211 schizophrenics and 247 healthy controls at our center. Five tag SNPs (single nucleotide polymorphisms) (rs4532, rs5326, rs2168631, rs6882300 & rs267418) within DRD1 gene were genotyped by TaqMan SNP genotyping assay. The positive...
