Article
Association of DRD2 gene variant with schizophrenia.
Neuroscience letters - 9 Jan 2006
Kukreti Ritushree, Tripathi Sudipta, Bhatnagar Pallav, Gupta Simone, Chauhan Chitra, Kubendran Shobhana, Janardhan Reddy Y C, Jain Sanjeev, Brahmachari Samir K
Abstract excerpt
Schizophrenia is a complex multifactorial disorder for which the pathobiology still remains elusive. Dysfunction of the dopamine D2 receptor signaling has been associated with the illness, but numerous studies provide confounding results. This study investigates the association of synonymous polymorphisms (His313 and Pro319) in the dopamine D2 receptor gene with schizophrenia using a case-control approach, with...
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