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Article

Pathway genetic load allows simultaneous evaluation of multiple genetic associations.

Burns : journal of the International Society for Burn Injuries - 1 Sept 2010

Huebinger Ryan M, Garner Harold R, Barber Robert C

Abstract excerpt

OBJECTIVE: Despite the general success of genome-wide association studies, much heritability remains unidentified in many disease states. Some of this 'missing' heritability may lie in epistatic interactions among multiple loci, which are typically ignored. We utilized a method for simultaneous evaluation of epistatic interactions between allelic variations within genes confined to a single pathway, which we have...

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Source

Identifiers

PMID: 20381257
DOI: 10.1016/j.burns.2010.02.001

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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