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Article

Genetic variants associated with sepsis.

PloS one - 1 Jan 2022

Engoren Milo, Jewell Elizabeth S, Douville Nicholas, Moser Stephanie, Maile Michael D, Bauer Melissa E

Abstract excerpt

BACKGROUND: The variable presentations and different phenotypes of sepsis suggest that risk of sepsis comes from many genes each having a small effect. The cumulative effect can be used to create individual risk profile. The purpose of this study was to create a polygenic risk score and determine the genetic variants associated with sepsis. METHODS: We sequenced ~14 million single nucleotide polymorphisms with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 35275946
DOI: 10.1371/journal.pone.0265052
PMCID: PMC8916629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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