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Article

Separating speed and ability to displace roadblocks during DNA translocation by FtsK.

The EMBO journal - 21 Apr 2010

Crozat Estelle, Meglio Adrien, Allemand Jean-François, Chivers Claire E, Howarth Mark, Vénien-Bryan Catherine, Grainge Ian, Sherratt David J

Abstract excerpt

FtsK translocates dsDNA directionally at >5 kb/s, even under strong forces. In vivo, the action of FtsK at the bacterial division septum is required to complete the final stages of chromosome unlinking and segregation. Despite the availability of translocase structures, the mechanism by which ATP hydrolysis is coupled to DNA translocation is not understood. Here, we use covalently linked translocase subunits to...

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Identifiers

PMID: 20379135
DOI: 10.1038/emboj.2010.29
PMCID: PMC2868570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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