Article
Effects of CYP2C19, MDR1, and interleukin 1-B gene variants on the eradication rate of Helicobacter pylori infection by triple therapy with pantoprazole, amoxicillin, and metronidazole.
European journal of clinical pharmacology - 1 Jul 2010
Gawrońska-Szklarz Barbara, Siuda Andrzej, Kurzawski Mateusz, Bielicki Dariusz, Marlicz Wojciech, Droździk Marek
Abstract excerpt
OBJECTIVE: Eradication of H. pylori is an important treatment strategy in peptic ulcer patients. Current regimens of eradication consist of proton pump inhibitor (PPI) and two antibiotics. Effects of PPI may depend on their metabolism, and other factors important for the pathophysiology of peptic ulcer disease. Aim of the present study was to evaluate an association of CYP2C19, MDR1, and IL-1B polymorphisms with...
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