Article
Polymorphism of interleukin-1beta affects the eradication rates of Helicobacter pylori by triple therapy.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Jan 2004
Furuta Takahisa, Shirai Naohito, Xiao Fang, El-Omar Emad M, Rabkin Charles S, Sugimura Haruhiko, Ishizaki Takashi, Ohashi Kyoichi
Abstract excerpt
BACKGROUND AND AIMS: Polymorphism in interleukin-1beta (IL-1beta) is associated with intragastric pH levels in Helicobacter pylori-positive subjects. Intragastric pH levels affect the activity of antibiotics against H. pylori in the stomach. The aim of this study was to investigate whether IL-1beta polymorphism is associated with eradication rates of H. pylori by triple therapy with a proton pump inhibitor (PPI),...
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