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Article

Randomized open trial for comparison of proton pump inhibitors in triple therapy for Helicobacter pylori infection in relation to CYP2C19 genotype.

Journal of gastroenterology and hepatology - 1 Jul 2002

Inaba Tomoki, Mizuno Motowo, Kawai Kozou, Yokota Kenji, Oguma Keiji, Miyoshi Masatsugu, Take Susumu, Okada Hiroyuki, Tsuji Takao

Abstract excerpt

BACKGROUND AND AIMS: Genetic polymorphism of cytochrome P450 (CYP) 2C19 influences the efficacy of Helicobacter pylori eradication therapy with a proton pump inhibitor (PPI) and amoxicillin. However, in triple therapy (PPI plus amoxicillin and clarithromycin), little is known about the impact of CYP2C19 polymorphism, or the use of rabeprazole, which is not well metabolized by CYP2C19. The efficacy of three PPI...

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Identifiers

PMID: 12121503
DOI: 10.1046/j.1440-1746.2002.02790.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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