Article
Interleukin-1beta genetic polymorphism influences the effect of cytochrome P 2C19 genotype on the cure rate of 1-week triple therapy for Helicobacter pylori infection.
The American journal of gastroenterology - 1 Nov 2003
Take Susumu, Mizuno Motowo, Ishiki Kuniharu, Nagahara Yasuhiro, Yoshida Tomowo, Inaba Tomoki, Yamamoto Kazuhide, Okada Hiroyuki, Yokota Kenji, Oguma Keiji, Shiratori Yasushi
Abstract excerpt
OBJECTIVES: Genetic polymorphism of interleukin (IL)-1beta is associated with differences in gastric acid suppression in response to Helicobacter pylori (H. pylori) infection. Thus, the polymorphism might affect H. pylori eradication therapy, as antibiotics used in treatment regimens may be acid sensitive. In this study, we examined the impact of IL-1beta genetic polymorphism on the cure rate of triple therapy...
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