Article
Fission yeast Rad26ATRIP delays spindle-pole-body separation following interphase microtubule damage.
Journal of cell science - 1 May 2010
Herring Matthew, Davenport Nick, Stephan Kendra, Campbell Shawna, White Rebecca, Kark Jonathan, Wolkow Tom D
Abstract excerpt
The conserved fission yeast protein Rad26(ATRIP) preserves genomic stability by occupying central positions within DNA-structure checkpoint pathways. It is also required for proper cellular morphology, chromosome stability and following treatment with microtubule poisons. Here, we report that mutation of a putative nuclear export sequence in Rad26(ATRIP) disrupted its cytoplasmic localization in untreated cells...
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