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Article

Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage.

Molecular biology of the cell - 1 May 2009

Loidl Josef, Mochizuki Kazufumi

Abstract excerpt

In the ciliate Tetrahymena, meiotic micronuclei (MICs) undergo extreme elongation, and meiotic pairing and recombination take place within these elongated nuclei (the "crescents"). We have previously shown that elongation does not occur in the absence of Spo11p-induced DNA double-strand breaks (DSBs). Here we show that elongation is restored in spo11Delta mutants by various DNA-damaging agents including ones that...

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Identifiers

PMID: 19297526
DOI: 10.1091/mbc.e08-10-1058
PMCID: PMC2675622

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ATR
ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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