Article
Fission yeast Rad26 responds to DNA damage independently of Rad3.
BMC genetics - 3 Apr 2003
Wolkow Tom D, Enoch Tamar
Abstract excerpt
BACKGROUND: The Rad26/Rad3 complex in fission yeast detects genotoxic insults and initiates the cell cycle arrest and recovery activities of the DNA damage checkpoint. To investigate how the Rad26/Rad3 complex performs these functions, we constructed and characterized Rad26-GFP. RESULTS: Rad26-GFP localized to approximately six nuclear dots in cycling cells. Following treatment with a DNA damaging agent,...
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