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Article

A novel role for the GTPase-activating protein Bud2 in the spindle position checkpoint.

PloS one - 1 Jan 2012

Nelson Scott A, Sanson Anthony M, Park Hay-Oak, Cooper John A

Abstract excerpt

The spindle position checkpoint (SPC) ensures correct mitotic spindle position before allowing mitotic exit in the budding yeast Saccharomyces cerevisiae. In a candidate screen for checkpoint genes, we identified bud2Δ as deficient for the SPC. Bud2 is a GTPase activating protein (GAP), and the only known substrate of Bud2 was Rsr1/Bud1, a Ras-like GTPase and a central component of the bud-site-selection pathway....

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Identifiers

PMID: 22558355
DOI: 10.1371/journal.pone.0036127
PMCID: PMC3338500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel role for the GTPase-activating protein Bud2 in the spindle position checkpoint.PMID 22558355Read ↗

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