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Article

Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion.

International journal of oncology - 1 May 2010

De Bock Charles Edo, Lin Zhen, Mekkawy Ahmed H, Byrne Jennifer A, Wang Yao

Abstract excerpt

The urokinase-type plasminogen activator receptor (uPAR) has diverse biological functions including roles in proteolysis, cell adhesion and cellular signaling. We identified a heat shock protein MRJ (DNAJB6) as a novel uPAR-interacting protein in a yeast two-hybrid screen and confirmed the interaction and co-localization by GST-pull down assays, and co-immunoprecipitation in cells transfected with MRJ. Endogenous...

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Share to Cell Adhesion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HSP40 Heat-Shock Proteins

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Share to Nerve Tissue Proteins

Share to Receptors, Urokinase Plasminogen Activator

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Source

Identifiers

PMID: 20372789
DOI: 10.3892/ijo_00000598

Genes

DNAJB6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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