Article
Isolation and characterisation of Haemophilus influenzae type b mutants defective in transferrin-binding and iron assimilation.
FEMS microbiology letters - 15 Jan 1991
Holland J, Towner K J, Williams P
Abstract excerpt
The quinone antibiotic streptonigrin was used to select mutants of Haemophilus influenzae type b defective in human transferrin binding. Compared with the parent wild-type strain (JKP1), mutant JKP5 was unable to bind transferrin whilst mutant JKP4 showed reduced binding. JKP5 appeared to lack an approximately 72 kDa transferrin-binding protein. Unlike JKP1, neither JKP4 nor JKP5 were able to acquire iron from...
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