Article
TonB is essential for virulence in avian pathogenic Escherichia coli.
Comparative immunology, microbiology and infectious diseases - 1 Mar 2012
Holden Karen M, Browning Glenn F, Noormohammadi Amir H, Markham Philip F, Marenda Marc S
Abstract excerpt
Avian pathogenic Escherichia coli (APEC) strains have multiple iron-uptake systems that facilitate adaptation to iron-restricted environments and are believed to assist in colonisation of the host. These systems include several TonB-dependent transporters of ferri-siderophores encoded by the chromosome and the large virulence plasmid common to APECs. The tonB gene of the virulent APEC strain E956 was replaced...
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