Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential utilization by Haemophilus influenzae of haemoglobin complexed to the three human haptoglobin phenotypes.

FEMS immunology and medical microbiology - 1 Apr 2006

Morton Daniel J, VanWagoner Timothy M, Seale Thomas W, Whitby Paul W, Stull Terrence L

Abstract excerpt

Haemophilus influenzae has an absolute requirement for heme, which may be supplied as the haemoglobin-haptoglobin complex. Utilization of haemoglobin-haptoglobin by H. influenzae is mediated by a family of proteins termed the haemoglobin-haptoglobin binding proteins (Hgps), of which a given strain may contain up to four genes. Human haptoglobin occurs in three phenotypes (1-1, 2-1 and 2-2). Using mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haemophilus Infections

Share to Haptoglobins

Share to Hemoglobins

Share to Phenotype

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 16553817
DOI: 10.1111/j.1574-695X.2006.00052.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential utilization by Haemophilus influenzae of haemoglobin complexed to the three human haptoglobin phenotypes.PMID 16553817Read ↗

Identification of a haem-utilization protein (Hup) in Haemophilus influenzae.Semantic proximity Read ↗

The heme-binding lipoprotein (HbpA) of Haemophilus influenzae: role in heme utilization.Semantic proximity Read ↗

Characterization of hgpA, a gene encoding a haemoglobin/haemoglobin-haptoglobin-binding protein of Haemophilus influenzae.Semantic proximity Read ↗

Examination of phase-variable haemoglobin–haptoglobin binding proteins in non-typeable Haemophilus influenzae reveals a diverse distribution of multiple variantsSemantic proximity Read ↗

Analysis of haptoglobin and hemoglobin-haptoglobin interactions with the Neisseria meningitidis TonB-dependent receptor HpuAB by flow cytometry.Semantic proximity Read ↗

Lipoprotein e(P4) is essential for hemin uptake by Haemophilus influenzae.Semantic proximity Read ↗

Purification of human haptoglobin 1-1, 2-1, and 2-2 using monoclonal antibody affinity chromatography.Semantic proximity Read ↗

A hemoglobin-binding outer membrane protein is involved in virulence expression by Haemophilus ducreyi in an animal model.Semantic proximity Read ↗

Isolation and characterisation of Haemophilus influenzae type b mutants defective in transferrin-binding and iron assimilation.Semantic proximity Read ↗

Complex Role of Hemoglobin and Hemoglobin-Haptoglobin Binding Proteins in Haemophilus influenzae Virulence in the Infant Rat Model of Invasive InfectionSemantic proximity Read ↗

Contribution of the major and minor subunits to fimbria-mediated adherence of Haemophilus influenzae to human epithelial cells and erythrocytes.Semantic proximity Read ↗

Effect of haptoglobin phenotypes on growth of Streptococcus pyogenes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.