Article
A functional tonB gene is required for both utilization of heme and virulence expression by Haemophilus influenzae type b.
Infection and immunity - 1 Jun 1994
Jarosik G P, Sanders J D, Cope L D, Muller-Eberhard U, Hansen E J
Abstract excerpt
Haemophilus influenzae is nearly unique among facultatively anaerobic bacteria in its absolute requirement for exogenously supplied heme for aerobic growth. In this study, a mutant analysis strategy was used to facilitate identification of H. influenzae cell envelope components involved in the uptake of heme. Chemical mutagenesis was employed to produce a mutant of a nontypeable H. influenzae strain unable to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.