Article
A functional tonB gene is required for both utilization of heme and virulence expression by Haemophilus influenzae type b.
Infection and immunity - 1 Jun 1994
Jarosik G P, Sanders J D, Cope L D, Muller-Eberhard U, Hansen E J
Abstract excerpt
Haemophilus influenzae is nearly unique among facultatively anaerobic bacteria in its absolute requirement for exogenously supplied heme for aerobic growth. In this study, a mutant analysis strategy was used to facilitate identification of H. influenzae cell envelope components involved in the up...
Topics
- Amino Acid Sequence
- Animals
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- Escherichia coli Proteins
- Genes, Bacterial
- Genetic Complementation Test
- Haemophilus influenzae
- Heme
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Rats
- Virulence