Article
Identification of a haem-utilization protein (Hup) in Haemophilus influenzae.
Microbiology (Reading, England) - 1 Dec 2004
Morton Daniel J, Smith Ann, Ren Zhen, Madore Larissa L, VanWagoner Timothy M, Seale Thomas W, Whitby Paul W, Stull Terrence L
Abstract excerpt
Haemophilus influenzae has an absolute growth requirement for a porphyrin source. This growth requirement can be satisfied in vitro by haem, haemoglobin or the haemoglobin-haptoglobin, haem-haemopexin and haem-albumin complexes. A family of proteins, termed the Hgp proteins, which are essential for utilization of the haemoglobin-haptoglobin complex, has previously been identified. A strain lacking the Hgp...
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