Article
Characterization of the hgbA locus encoding a hemoglobin receptor from Haemophilus ducreyi.
Infection and immunity - 1 Jun 1995
Elkins C, Chen C J, Thomas C E
Abstract excerpt
Haemophilus ducreyi can bind hemoglobin and use it as a source of heme, for which it has an obligate requirement. We previously identified and purified HgbA, a hemoglobin-binding outer membrane protein from H. ducreyi. In this report, we describe the molecular cloning, expression, DNA sequence, and mutagenesis of the structural gene for HgbA, hgbA. H. ducreyi and recombinant Escherichia coli expressing hgbA bound...
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