Article
Haemophore-mediated bacterial haem transport: evidence for a common or overlapping site for haem-free and haem-loaded haemophore on its specific outer membrane receptor.
Molecular microbiology - 1 Jul 2001
Létoffé S, Deniau C, Wolff N, Dassa E, Delepelaire P, Lecroisey A, Wandersman C
Abstract excerpt
Bacterial extracellular haemophores also named HasA for haem acquisition system form an independent family of haemoproteins that take up haem from host haeme carriers and shuttle it to specific receptors (HasR). Haemophore receptors are required for the haemophore-dependent haem acquisition pathway and alone allow free or haemoglobin-bound haem uptake, but the synergy between the haemophore and its receptor...
Topics
- Apoproteins
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Binding Sites
- Biological Transport
- Carrier Proteins
- Escherichia coli
- Heme
- Heme-Binding Proteins
- Hemeproteins
- Membrane Proteins
- Mutation
- Protein Binding