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Article

Two alternative binding mechanisms connect the protein translocation Sec71-Sec72 complex with heat shock proteins.

The Journal of biological chemistry - 12 May 2017

Tripathi Arati, Mandon Elisabet C, Gilmore Reid, Rapoport Tom A

Abstract excerpt

The biosynthesis of many eukaryotic proteins requires accurate targeting to and translocation across the endoplasmic reticulum membrane. Post-translational protein translocation in yeast requires both the Sec61 translocation channel, and a complex of four additional proteins: Sec63, Sec62, Sec71, and Sec72. The structure and function of these proteins are largely unknown. This pathway also requires the cytosolic...

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PMID: 28286332
DOI: 10.1074/jbc.M116.761122
PMCID: PMC5427277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Two alternative binding mechanisms connect the protein translocation Sec71-Sec72 complex with heat shock proteins.PMID 28286332Read ↗

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