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Article

Overcharging below the nanoscale: multivalent cations reverse the ion selectivity of a biological channel.

Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Feb 2010

García-Giménez Elena, Alcaraz Antonio, Aguilella Vicente M

Abstract excerpt

We report charge inversion within a nanoscopic biological protein ion channel in salts of multivalent ions. The presence of positive divalent and trivalent counterions reverses the cationic selectivity of the OmpF channel, a general diffusion porin located in the outer membrane of E. coli. We discuss the conditions under which charge inversion can be inferred from the change in sign of the measured quantity, the...

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PMID: 20365600
DOI: 10.1103/PhysRevE.81.021912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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