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Article

Chemical modification of the bacterial porin OmpF: gain of selectivity by volume reduction.

Biophysical journal - 15 Feb 2006

Vrouenraets Maarten, Wierenga Jenny, Meijberg Wim, Miedema Henk

Abstract excerpt

OmpF is an essentially nonselective porin isolated from the outer membrane of Escherichia coli. Here we report on the manipulation of the ion selectivity of OmpF by chemical modification with MTS reagents (MTSET, MTSEA, and MTSES) and the (rather bulky) tripeptide glutathione, all cysteine specific. When recorded in a gradient of 0.1//1 M CaCl2 or 0.1//1 M NaCl, pH 7.4 solutions, measured reversal potentials of...

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Identifiers

PMID: 16299071
DOI: 10.1529/biophysj.105.072298
PMCID: PMC1367271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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